Endothelial Progenitor Cells: Novel Biological Marker for Risk Stratification in Arterial Hypertension?
نویسندگان
چکیده
منابع مشابه
Novel biomarkers for risk stratification in pulmonary arterial hypertension
Risk stratification in pulmonary arterial hypertension (PAH) is paramount to identifying individuals at highest risk of death. So far, there are only limited parameters for prognostication in patients with PAH. 95 patients with confirmed PAH were included in the present analysis and followed for a total of 4 years. Blood samples were analysed for serum levels of N-terminal pro-brain natriuretic...
متن کاملCell Therapy for Pulmonary Arterial Hypertension: Potential Efficacy of Endothelial Progenitor Cells and Mesenchymal Stem Cells
Duncan J. Stewart, MD Sprott Centre for Stem Cell Research The Ottawa Hospital Research Institute & University of Ottawa Ottawa, Ontario, Canada Pulmonary arterial hypertension (PAH) presents a challenging problem for health care providers, as effective long-term therapies have been elusive. An emerging paradigm for the pathogenesis of PAH is that endothelial cell injury and apoptosis at the le...
متن کاملCharacterization of altered patterns of endothelial progenitor cells in sickle cell disease related pulmonary arterial hypertension
Endothelial dysfunction plays an important role in the pathogenesis of pulmonary arterial hypertension (PAH) in sickle cell disease (SCD). A variety of evidence suggests that circulating endothelial progenitor cells (EPCs) play an integral role in vascular repair. We hypothesized that SCD patients with PAH are deficient in EPCs, potentially contributing to endothelial dysfunction and disease pr...
متن کاملCirculating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension
Background—Impaired endothelial homeostasis underlies the pathophysiology of pulmonary arterial hypertension (PAH). We speculated that PAH patients are deficient in circulating endothelial progenitor cells (EPCs), potentially contributing to endothelial dysfunction and disease progression. Methods and Results—We recruited 41 patients with Eisenmenger syndrome (13 with Down syndrome), 55 with id...
متن کاملEndothelial progenitor cells as a cardiometabolic risk factor marker in prediabetes.
OBJECTIVE Endothelial progenitor cells (EPCs) have recently been considered as a potential novel marker of vascular integrity, atherosclerosis and cardiovascular risk. This study was performed to investigate the main determinants of EPC levels in individuals with prediabetes. DESIGN Thirty-nine participants with newly diagnosed prediabetes were enrolled. Flow cytometric analysis was used to q...
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ژورنال
عنوان ژورنال: Biomedical Journal of Scientific & Technical Research
سال: 2019
ISSN: 2574-1241
DOI: 10.26717/bjstr.2019.14.002566